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differential management rheumatology algorithm causes blood coagulation dic disorders disseminated erythematosus fever immunecompromised immunocompromised intravascular leukemia lupus markers myelitis neurology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
and Differential Diagnosis ... Lymphadenopathy, CNS ... or λ), Smudge Cells ... Blood #Disorders #hematology ... #Differential #Diagnosis
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Parotid swelling CNS ... nervous system (CNS ... peripheral neuropathy, transverse ... • 8%-27% for CNS ... Nephrogenic DI Hematologic
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... : Granulocytic cells ... leukostasis syndrome: CNS ... #Leukemia #Hematology ... #Oncology #Diagnosis
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... bouts of HTN Diagnostic ... Myelitis Diagnosis ... Pleocytosis > 100 cells ... #Myelitis #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Thromboembolism (7%) • CNS ... Schistocytes, helmet cells ... #Coagulation #diagnosis ... treatment #management #hematology
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm Structural Defect - Asplenia/HypospIenism • Bacteremia/Septic
- Differential Diagnosis ... Mediated Immunity - T-Cells ... jirovecii • CNS ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... and CNS • Headache ... neuropathy • Transverse ... vein thrombosis Hematologic ... Erythematosus #Diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... Vasculitis Differential Diagnosis ... Multinucleated giant cells ... chorioretinitis, CNS ... #Rheumatology
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