24 results
Localizing Extraocular Movement Disorders
 • CN Ill (Oculomotor) Nerve Palsy 
 • CN IV (Trochlear) Nerve
Movement Disorders • CN ... Nerve Palsy • CN ... Nerve palsy • CN ... One-and-a-half Syndrome ... #diagnosis #ocular
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
desaturation, Scotoma, Ocular ... Other brainstem syndromes ... Many others • Transverse ... pain • Extra-CNS ... erythematosus, Sjögren syndrome
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
Short Stature - Differential ... • Turner Syndrome ... Anorexia Nervosa • CNS ... #ShortStature #Differential ... endocrinology #causes #pediatrics
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
ulceration • Ocular ... basal ganglia, CNS ... meningitis), MCC CNS ... Behcet disease) Differential ... collaboration • CNS
Hyponatremia - Differential Diagnosis Algorithm
Hypovolemic - Give volume
Hypervolemic (Edematous) - Look for and treat underlying cause
Hyponatremia - Differential ... cirrhosis, nephrotic syndrome ... Stress, Nausea, Pulmonary ... Diseases, CNS Disease ... #Hyponatremia #Differential
Hyponatremia - Differential Diagnosis by Mechanism
Decr Blood Pressure (“Decr Effective Circulating Volume”) 
 - Volume depletion
Hyponatremia - Differential ... - Cirrhosis Syndrome ... the lung) - CNS ... hemorrhage) - Pulmonary ... #Hyponatremia #Differential
Approach to the A-a Gradient
A-a gradient = PAO2 - PaO2
A-a gradient = [FiO2 x (Patm -
Hypoventilation: CNS ... Hypoventilation Syndrome ... Intracardiac, Pulmonary ... Hepatopulmonary Syndrome ... Hypoxia #hypoxemia #differential
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Scleromyxedema (CNS ... +GI+CVS+joints) ... +PNS+GI+Endocrine ... Hypergammaglobulinemic macular ... Hematology #Monoclonal #Differential
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... disorder (Cardiac, pulmonary ... etc) • CNS -> ... • Acute stroke syndromes ... #Weakness #Differential
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
gland) biopsy • Ocular ... Parotid swelling CNS ... nervous system (CNS ... peripheral neuropathy, transverse ... • 8%-27% for CNS