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neurology rheumatology aids als amyotrophic barre cauda caudaequina causes compylobacterjejuni equina erythematosus flaccidpalsy gbs gitelman guillain guillainbarre guillainbarresyndrome hematology hiv
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Weakness - Differential ... Diagnosis Framework ... pulmonary etc) • CNS ... Polymyositis • Immune ... #Diagnosis #neurology
Guillain–Barré syndrome (GBS) (aka: Landry–Guillain–Barré–Strohl syndrome:  Most common cause of acute flaccid paralysis  Rapidly progressive ascending paralysis & areflexia  Autonomic
Guillain–Barré syndrome ... Differential diagnosis ... Multiple Sclerosis: CNS ... prominent cranial nerve ...  Transverse myelitis
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
HIV / AIDS - Differential ... Diagnosis Framework ... required until immune ... of the abducens nerve ... #Infections #differential
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
activation of an immune ... that results in CNS ... brain and/or optic nerve ... #management #neurology ... #differential
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Pathophysiology: • Immune ... • Weakness: Starts ... • Pain: Due to nerve ... Guillain-Barre Diagnosis ... #diagnosis #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Diagnosis: • Dry ... myelopathy, cranial nerve ... peripheral neuropathy, transverse ... • 8%-27% for CNS ... #Management
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
compression of nerve ... (CES) is usually ... Diagnosis: • ... myelopathy • Transverse ... #differential #
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... Pinpoint-sized red spots ... Significance (IDUS) • Immune ... blood count with differential ... #diagnosis #hematology
Neurological Manifestations of Tuberculosis Spinal Arachnoiditis & Polyradiculopathy: • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
spinal cord and nerve ... Reconstitution Inflammatory Syndrome ... or abruptly • CN ... #Tuberculosis #diagnosis ... #differential #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Diagnosis Framework ... Multinucleated giant cells ... muscle weakness • Nerves ... chorioretinitis, CNS
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