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differential management hematology signs vasculitis abnormal activation atlas autoimmune beaus behcet cauda caudaequina causes classification clinical compylobacterjejuni disease diseases equina
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
neuropathy) • Systemic ... Scleromyxedema (CNS ... (Thrombosis in vascular ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... basal ganglia, CNS ... meningitis), MCC CNS ... and diplopia) • Vascular ... signs #symptoms #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... (CNS) dysfunction ... Liver function tests ... #Diagnosis #Management ... #Hematology #Rheumatology
Guillain–Barré syndrome (GBS) (aka: Landry–Guillain–Barré–Strohl syndrome:  Most common cause of acute flaccid paralysis  Rapidly progressive ascending paralysis & areflexia  Autonomic
Guillain–Barré syndrome ... sensory and motor systems ... Differential diagnosis ... Multiple Sclerosis: CNS ...  Transverse myelitis
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
(CES) is usually ... myelopathy • Transverse ... lumbar stenosis • Vascular ... • Provocative Tests ... absent anal wink test
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... and CNS • Headache ... neuropathy • Transverse ... #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Diagnosis: • Dry ... Parotid swelling CNS ... peripheral neuropathy, transverse ... • 8%-27% for CNS ... #Rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... Vasculitis Differential Diagnosis ... pulse deficits vascular ... chorioretinitis, CNS ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... and bullous or vesicular ... • Cogan Syndrome ... retinopathy Lab Tests ... #rheumatology #
Nail Pathologies - Findings in or Near Nails Paronychia A superficial infection of the proximal and lateral
Systemic causes ... nail growth from systemic ... seen in Reiter's syndrome ... Abnormal #Pathology #Diagnosis ... Clinical #Signs #PhysicalExam
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