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diagnosis hematology anemia neurology amenorrhea endocrinology extravascular gynecology hemolysis intravascular obgyn weightloss agglutinin aiha autoimmune cardiology chf chronic clinical cold
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin ... AIHA Primary Secondary ... Secondary Cold ... Positive Coombs testing ... younger pts) Differential
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... - Differential ... Diagnosis Algorithm ... Warm AIHA • Cold ... Complement-Mediated • Cold
Causes of Secondary IgA Nephropathy - Differential Diagnosis Algorithm • GI disorders: Celiac disease, Crohn's disease,
Causes of Secondary ... Nephropathy - Differential ... Diagnosis Algorithm ... • GI disorders ... : COPD, cystic fibrosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... Autoimmune (AIHA)"Cold ... (e.g. primary cold ... lymphoproliferative disorders ... #differential #
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia Focal Hyporeflexia: • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Reflex Testing - ... , Acute spinal cord ... finding in spinal cord ... #Causes #differential ... #diagnosis #table
Causes of Pulmonary Hypertension - Differential Diagnosis Algorithm Pulmonary Arterial Hypertension • Idiopathic • Associated with:
Causes of Pulmonary ... Hypertension - Differential ... Diagnosis Algorithm ... Hypoxemia: • COPD ... #Causes
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... Diagnosis Algorithm ... Agglutination - Cold ... Consider RBC membrane disorder ... workup #hematology #testing
Autoimmune Hemolytic Anemia (AIHA) WARM AHA - Primary - Idiopathics - Secondary Infectious • Viral- HIV, EBV, HCV, HEV •
Autoimmune Hemolytic ... alpha-methyldopa COLD ... #Autoimmune #Hemolytic ... AIHA #Diagnosis #Differential ... #Algorithm
Secondary Causes of Hypothermia - Differential Diagnosis Framework Definition: - Core temp < 35°C Infectious: - Sepsis Neuromuscular Disease: -
Secondary Causes ... Definition: - Core ... neuropathies - Spinal cord ... injuries Skin Disorders ... #Causes
Causes of Chronic Dyspnea - Differential Diagnosis Algorithm Pericardial • Effusion • Cardiac Tamponade* • Constriction Myocardial •
Dyspnea - Differential ... Diagnosis Algorithm ... Artery Disease • Stable ... • Asthma • COPD ... Pneumonia • ARDS • COPD
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