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dermatology differential leukemia chronic lymphocytic mgus workup adultonset antinxp2 antinxp2dm arteritis cell classification dermatologic dermatomyositis disease erythematosus gammopathies gammopathy gca
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... Pseudohyponatremia • ↓anion gap ... • CRAB • Hyperviscosity ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Multiple Myeloma and Monoclonal ... Look for gamma gap ... if this is is monoclonal ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
cancer for which ... Bone lesions (CRAB ... to the plasma cell ... #Significance #hematology ... #diagnosis #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... lymphoid organs When Cancer ... -> Invade Skin: ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... Hepatomegaly • Skin ... Diagnosis: • ... #workup #oncology ... #hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Maculopapular rash ... Differential Diagnosis ... syndrome • Giant cell ... #dermatology #rash ... #diagnosis #rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Arthralgia/arthritis, Skin ... rash ± odynophagia ... hemopathies, solid cancers ... #management #treatment ... #rheumatology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... general feeling of ill ... , breast CA - Hematologic ... #dermatology #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
fludarabine) 3) Monoclonal ... uw_IMresidency #CLL ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
gammopathy, and skin ... ovarian tumors, lung cancers ... gastric tumors • Hematology ... #differential #diagnosis ... #hematology
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