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diagnosis rheumatology lupus sle activation adultonset antinxp2dm comparison druginduced erythematosus hematology lyme macrophage mas monkeypox stages stills summary syndrome syphilis
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... arthritis, Skin rash ... • Ocular: uveitis ... #diagnosis #management ... #treatment #rheumatology
Monkeypox What? Monkeypox virus belongs to the family Poxviridae, subfamily Chordopoxvirinae, and genus orthopoxvirus Viral zoonotic disease that is
Viral zoonotic disease ... Characteristic Rash ... Umbilification - Rash ... three weeks Clinical ... #Dermatology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
(blue-purple) rash ... • Erythematous rash ... had more severe disease ... #AntiNXP2 #Dermatomyositis ... #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... - pANCA anti-MPO ... life-threatening • Treatment ... Evolution: Chronic disease
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... - pANCA anti-MPO ... Manifestations: Malar rash ... Evolution: Chronic disease
Lyme Disease - Diagnosis and Management Summary Lyme Disease Epidemiology: - Spirochete - Reservoir: small mammals & birds - Transmitted
and Management ... Clinical Progression ... Pericarditis • Ocular ... Rash: distinctive ... #treatment
Syphilis - Clinical Manifestations and Treatment 1) Primary Syphilis • Direct lesion contact during sex is responsible
Syphilis - Clinical ... loss • Skin: Rash ... meningovascular disease ... Coronary artery disease ... stages #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
fever syndromes Clinical ... Fever is the main clinical ... Petechial or purpuric rash ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management
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