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diagnosis differential management treatment lupus sle systemic activation algorithm alice arthritis bee bells cerebritis disease headache hematology hyperkalemia hyperthermic k
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... Lumbar Puncture, EEG ... #SLE #CNS #neurology ... #rheumatology #
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
(e.g. oculomotor ... AQP4-lgG disease; e.g ... pain • Extra-CNS ... Systemic lupus erythematosus ... Manifestations #diagnosis #neurology
Alice in Wonderland Syndrome What? Metamorphophsia - Distortions of the visual perceptions with changes in size (micro
in Wonderland Syndrome ... • CNS: parietal ... • Infection (e.g ... Brain lesions (e.g ... #diagnosis #neurology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... • Malignancy (e.g ... Endocrine disorders (e.g ... and CNS • Headache ... #Diagnosis #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Systemic lupus erythematosus ... nervous system (CNS ... underlying disease (eg ... • Infection (eg ... #Rheumatology
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy Presentation:
Diagnosis and Workup ... No additional workup ... sarcoid or other CNS ... inflammatory cause) • EMG ... Management #Treatment #Neurology
Approach to Headaches - Differential Diagnosis Algorithm Red flags (PHANTOMS): • Pattern change, progressively worse, papilledema •
papilledema • Horner syndrome ... symptoms and signs (e.g ... brain lesion • CNS ... infection (e.g. ... Diagnosis #Algorithm #neurology
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
pulmonary etc) • CNS ... • Acute stroke syndromes ... dystrophies Work ... electromyographic (EMG ... Differential #Diagnosis #neurology
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
BEE Syndromes - ... nervous system (CNS ... skull neoplasms (e.g ... recessive—Usher syndrome ... #neurology #noninflammatory
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
unit activity on EMG ... of diazepam • EMG ... antibody that works ... TPO, TTG, etc EMG ... Management #treatment #neurology
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