17 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Cerebrovascular Disease ... Puncture, EEG Treatment ... #neurology #rheumatology ... diagnosis #management #treatment
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute cutaneous ... scarring • Subacute cutaneous ... Malignancy (e.g. hematologic ... involve PNS and CNS ... inflammation Cutaneous
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Rare (SSA+ for cutaneous ... constitutional symptoms • Treatment ... rare), Topics for cutaneous-DIL ... life-threatening • Treatment ... Evolution: Chronic disease
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... gangrenosum • Cutaneous ... to cold IgG • Lupus ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Systemic lupus ... nervous system (CNS ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
vasculitis) • Cutaneous ... basal ganglia, CNS ... meningitis), MCC CNS ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
transformation) Treatment ... Waiting" →several RCTs ... chemotherapy for low-risk disease ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Cutaneous larva migrans skin Rash
25 F recent Caribbean vacation, walked barefoot on sand and now with
No treatment is ... rates of recurrent disease ... effective, and its ... University Infectious Diseases ... migrans #skinRash #dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
inflammation Others: • Lupus ... aphthous ulcers, cutaneous ... such as systemic lupus ... strong sign of cutaneous ... • ANA (Suggest CTD
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... Most common extra cutaneous ... ’s syndrome - Lupus ... Treatment: - Systemic ... #oncology