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diagnosis rheumatology management differential activation acute antinxp2 antinxp2dm bee behcet cerebritis cns criteria dermatologic dermatomyositis dermatosis febrile gpa granulomatosis inflammatory
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
nervous system (CNS ... and less common diseases ... diagnosis and treatment ... Systemic lupus erythematosus ... #neurology #inflammatory
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Systemic Lupus Erythematosus ... Demyelinating Syndrome ... Cerebrovascular Disease ... #SLE #CNS #neurology ... #rheumatology #
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
commonly through its ... purpuric macules • Erythematous ... • Ulcerated, erythematous ... • Goodpasture syndrome ... Polyangiitis #GPA #dermatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Systemic lupus erythematosus ... nervous system (CNS ... systemic lupus erythematosus ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis) Major criteria 1. Abrupt onset of tender
onset of tender erythematous ... inflammatory disease ... Excellent response to treatment ... Criteria #Diagnosis #Hematology ... #Dermatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... basal ganglia, CNS ... meningitis), MCC CNS ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... et diutinum Neurologic ... +GI+CVS+joints) ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
affects the skin, neurologic ... ischemia • Skin: Erythematous ... cognitive impairment, neurologic ... vasculitis • Behcet syndrome ... vasculitis • Cogan syndrome
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
subcutaneous edema Pts ... with edema • Erythematous ... had more severe disease ... positive patients Treatment ... #dermatology
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