8 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... solid cancers • Systemic ... Prunelle Getten #AdultOnset ... #diagnosis #management ... #treatment #rheumatology
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome - Treatment ... Ulcers: • Treatment ... case by case) • Surgery ... #management #pharmacology ... #rheumatology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's Disease ... episode (30%) Systemic ... BrighamChiefs #AdultOnset ... #diagnosis #management ... #treatment
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
of Systemic Lupus ... Cerebrovascular Disease ... #neurology #rheumatology ... cerebritis #diagnosis #management ... #treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
highly inflammatory disease ... (CNS) dysfunction ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome Systemic ... basal ganglia, CNS ... Arthritis, AS Treatment ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Central nervous system ... Nephrogenic DI Hematologic ... Cytopenia: 2% Systemic ... Adenocarcinoma Treatment ... #Diagnosis #Management
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
synovitis after surgery ... Acute Pseudogout: Treatment ... polyarticular CPPD • Systemic ... #Rheumatology # ... diagnosis #management