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diagnosis rheumatology management differential erythematosus neurology oncology sle systemic activation bee behcet cerebritis classification cns dermatology inflammatory macrophage mas monoclonal
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
nervous system (CNS ... and less common diseases ... diagnosis and treatment ... • Systemic lupus ... ANCA-associated vasculitides
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... Puncture, EEG Treatment ... #neurology #rheumatology ... diagnosis #management #treatment
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... : • Behçet Syndrome ... • Cogan Syndrome ... such as systemic lupus ... • ANA (Suggest CTD
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
ANCA-associated vasculitis ... Malignancy (e.g. hematologic ... • Mesenteric vasculitis ... involve PNS and CNS ... vein thrombosis Hematologic
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... Autoimmunity: • -MM/WM: Vasculitis ... to cold IgG • Lupus ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
, small-vessel vasculitis ... panuveitis, retinal vasculitis ... MCC-small vessel vasculitis ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... nervous system (CNS ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... ) • Cutaneous vasculitis ... Nephrogenic DI Hematologic ... : 2% Systemic Vasculitis ... Adenocarcinoma Treatment
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... , breast CA - Hematologic ... Leukocytoclastic vasculitis ... - Lupus - Leukemia ... Treatment: - Systemic
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
including systemic lupus ... ANCA-associated vasculitis ... , Lyme disease, ... Hypoalbuminemia Treatment ... diagnosis #management #rheumatology
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