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diagnosis management differential algorithm anticoagulation breakthrough cerebritis chronic cll cns differentiation erythematosus essential et leukemia lupus lymphocytic mds monoclonal myelodysplasia
Recurrent / Breakthrough DVT During Anticoagulation Subtherapeutic Anticoagulation Hypercoagulable State - Antithrombin deficiency - Hypercoagulability ot
/ Breakthrough DVT ... Hypercoagulability ot Ca ... Behcet's disease - APLS ... - May-Thurner syndrome ... anticoagulation #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... Triggers: ATRA treatment ... #management #hematology ... #oncology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Puncture, EEG Treatment ... (for secondary APS ... prevention (statin for CVA ... CNS #neurology #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Scleromyxedema (CNS+GI+CVS ... • Amyloidosis (CVS ... beds-renal, retinal, DVT ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
microglobulin Treatment ... • Richter’s Syndrome ... Transform to DLBCL, PML ... diagnosis #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Antibiotics such as ... factor (GCSF) treatments ... marrow studies Treatment ... #diagnosis #hematology ... #oncology
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
MI, stroke, DVT/ ... transformation into MDS or AML ... patients with no CV ... Thrombocythemia #ET #hematology ... diagnosis #management #hematology
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