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diagnosis hemolysis hus cardiology causes comparison endocarditis extravascular hemolytic hemolyticuremicsyndrome intravascular management microangiopathies monoclonal oncology paraproteinemias primary purpura schistocytes thrombocytopenia
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table • Thrombotic Thrombocytopenic Purpura (TTP)
Thrombotic Microangiopathies ... - Primary Thrombotic ... Diagnosis Table ... • Thrombotic ... #TMA #hematology
Thrombotic Microangiopathy - TTP VS HUS Big picture points : Often hard to differentiate the two entities,
Thrombotic Microangiopathy ... Often hard to differentiate ... testing for TTP #Thrombotic ... Comparison #Diagnosis #Table ... #Hematology
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
hemolysis: • Thrombotic ... - Drug-induced thrombotic ... microangiopathy ... macroangiopathic hemolytic anemia ... #diagnosis #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
hemolytic anemia ... syndrome - Thrombotic ... : Thrombotic thrombocytopenic ... Extravascular #Causes #differential ... #diagnosis #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Organomegaly+↑RBC/plt+, ↑thrombosis ... (-) hemolytic anemia ... Hyperviscosity (Thrombosis ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Vascular: • Systemic ... Marantic (NTBE) Differential ... • Nonbacterial thrombotic ... Leukocytosis, anemia ... underlying cause + Systemic
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