863 results
COVID-19 Life Cycle

#COVID19 #LifeCycle #Timeline #Pathophysiology #Diagnosis
Cycle #COVID19 #LifeCycle ... #Timeline #Pathophysiology
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... Phosphorus -> Ca-Phos ... urine pH) • Ca-Phos ... Syndrome #TLS #Pathophysiology
Vitamin D Metabolism
Fat-soluble vitamin
Sources: dermal synthesis and food (dairy products, fish)
Active form: calcitriol (1,25-OH Vitamin D)
Main
absorption of Ca ... endocrinology #pathophysiology
Calcium Electrolyte Repletion
Always correct Ca for albumin before deciding if it is abnormal
Always correct Ca ... Corrected Ca ... = Measured Ca +
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
activation (↓ cAMP and Ca ... receptors, and Ca ... MOA: Block slow Ca ... channels to prevent Ca ... Classification #Classes #pathophysiology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Plateau Phase • Ca ... leading to slow Ca ... receptors, and Ca ... MOA: Block slow Ca ... Classification #Classes #pathophysiology
Tumor markers in clinical practice
Colorectal - CEA
Hepatocellular - AFP
Pancreatic - CA 19-9
Ovarian - CA 125
Breast -
Pancreatic - CA ... 19-9 Ovarian - CA ... 125 Breast - CA
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome Pathophysiology ... Contraction → ↑ Renin ↑ Ca ... Gitelman #Syndrome #Pathophysiology
Leishmaniasis Life Cycle
1) Sandfly takes a blood meal (injects promastigote stage into the skin)
Human Stages:
2) Promastigotes
Leishmaniasis #LifeCycle ... #diagnosis #pathophysiology
Diabetes Pathophysiology and Medication Targets

The ominous octet is one concept that summarizes the different pathophysiologic pathways
Diabetes Pathophysiology ... the different pathophysiologic ... #Diabetes #Pathophysiology