60 results
Adjuvant therapies in critical care: steroids to treat infectious diseases
 - Severe Community Acquired Pneumonia
steroids to treat infectious ... respiratory distress syndrome ... Corticosteroids #Adjuvant #InfectiousDiseases ... #Infections #Pharmacology ... #Management #Treatment
IDSA Algorithm for the Management of Purulent skin and soft tissue infections (SSTIs). 
Mild infection: for
with systemic signs ... with systemic signs ... 12 000 or <400 cells ... with systemic signs ... oral antibiotic treatment
Problem Representation - Approach to the Infectious Disease Patient

Who: Patient age and host/risk factors (such as
Approach to the Infectious ... illness What: Key signs ... define the clinical syndrome ... febrilepodcast@gmail.com #InfectiousDiseases
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... organ damage • Treatment ... : • Pathophysiology ... Lysis of tumor cells
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Activation of CD8 T cells ... Phagocytosis of blood cells ... Unknown cause Treatment ... diagnosis #management #treatment
Hantavirus
Pathogen: Hantavirus - Rodents are the primary reservoir
Transmission:
 • Shed in the urine, feces, saliva of
common route of infection ... Cardiopulmonary Syndrome ... • Autopsy PCR Treatment ... diagnosis #management #treatment ... #microbiology #infectiousdiseases
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... risk-stratification • Risks: infection ... only curative treatment ... Myelodysplastic #Syndrome
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
Signs of immunodeficiency ... humoral immunity Signs ... susceptibility to infection ... especially bacterial infections ... Agammaglobulinemia #XLinked #pathophysiology
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... epidural hematoma • Infection ... lumbar spine Signs ... #CaudaEquina #Syndrome ... #MSK #pathophysiology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophilia, 500-1,500 cells ... drug reaction, infection ... Strongyloides infection ... glucocorticoid treatment ... organ-specific signs