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diagnosis differential symptoms management syndrome arteritis autoimmune behcet disease disorders extraocular gca giantcell headache hematology immune inflammatory iris localization monoclonal
Clinical Manifestations of Serotonin Syndrome • Ophthalmologic: Mydriasis, Ocular clonus (slow horizontal movements) • Gastrointestinal: Diarrhea,
Clinical Manifestations ... Serotonin Syndrome • Ophthalmologic ... : Mydriasis, Ocular ... Diaphresis, flushing • CNS ... Symptoms #spectrum #signs
Localizing Extraocular Movement Disorders • CN Ill (Oculomotor) Nerve Palsy • CN IV (Trochlear) Nerve
Nerve Palsy • CN ... Skew Deviation Casey ... #Localization #ophthalmology ... #neurology #differential ... #diagnosis #ocular
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
NMO) - Clinical Manifestations ... desaturation, Scotoma, Ocular ... pain • Extra-CNS ... #diagnosis #neurology ... #symptoms #signs
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
M > F Clinical Manifestations ... ulceration • Ocular ... skin injury) • Neurologic ... spondyloarthritis • Ocular ... Leukemia, Lymphoma Ocular
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
& Mu) Skin Manifestations ... et diutinum Neurologic ... Manifestations: ... Scleromyxedema (CNS ... Hypergammaglobulinemic macular
Photophobia and Headache - Differential Diagnosis Framework Why? • The coexistence of photophobia and headache suggests the potential
meningeal irritation signs ... glaucoma - Ocular ... Trochlear headache • CNS ... differential #diagnosis #ophthalmology ... #Neurology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... tract, and often causes ... pulmonary disease, and ocular ... ulcers, cutaneous, ocular ... Cogan syndrome: Ocular
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... Manifestations depend ... systemic sx + signs ... them, but urgent rheumatology ... required +/- prompt ophthalmology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
noncompliance • Clinical manifestations ... pleural effusions, CNS ... skin lesions, ocular ... Zoster flare, ocular ... Parvovirus B19 • Candida
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... Extramuscular manifestations ... statins - probably caused
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