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diagnosis differential endocarditis fungal microbiology cardiology comparison infective negative bcnie causes infections management pathology algorithm bloodculture bloodcultures clinical cnie dermatology
Fungal Pneumonias - Diagnosis Comparison Table • Aspergillus • Blastomyces • Candida • Coccidioides • Cryptococcus
Diagnosis Comparison Table ... • Aspergillus ... Blastomyces • Candida ... Diagnosis #Comparison #Table ... #microbiology #infectiousdiseases
Microorganisms Responsible for Infective Endocarditis Native valves: - Streptococcus viridans - Enterococci - Other streptococci
bacilli - Fungi (Candida ... , Aspergillus, Histoplasma ... ) - Culture negative ... #Endocarditis #Bacteria ... #Differential #InfectiousDiseases
My Patient with Infective Endocarditis (IE) Has Negative Blood Cultures - Did they receive antibiotics prior
Negative Blood Cultures ... have a fastidious bacteria ... this be a non-bacterial ... Fungal (Histoplasma/Aspergillus ... patient a surgical candidate
Causes of blood culture negative infective endocarditis Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
Causes of blood culture ... whipplei, Fungi (Aspergillus ... , Candida), Mycoplasma ... under BCNIE, these bacteria ... #Endocarditis #InfectiousDiseases
Transplant Infections Timeline Pre-transplant: • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut) • Viruses: HSV (reactivation) Engraftment:
Pre-transplant: • Common bacteria ... gut) • Fungi: Candida ... (mucosa), Aspergillus ... RSV • Fungi: Aspergillus ... diagnosis #causes #infectiousdiseases
Blood Culture-Negative Infective Endocarditis (BCNIE) Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... separate blood cultures ... whipplei, Fungi (Aspergillus ... , Candida), Mycoplasma ... differential #workup #infectiousdiseases
Differential diagnosis of Skin + Eye infections • Bacterial: Staph spp, Strep spp, Pseudomonas spp, Bartonella,
infections • Bacterial ... HIV • Fungal: Candida ... spp, Aspergillus ... #dermatology #InfectiousDiseases
Common Fungal Pathology • Candida - Small yeast intermingled with pseudohyphae • Aspergillosis - Septate
Pathology • Candida ... Pathology #clinical #microscopy ... #table #atlas #
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Hypercoagulable (APLAS ... 90% of IE cases Culture ... Tropheryma Whipplei • Aspergillus ... • Blood cultures ... • Persistent bacteremia
Important Fungal Stains Mycology Lab: • Calcofluor white - Fluorochrome that binds glucans and chitin in fungal
preparation from culture ... exceptions are Aspergillus ... #microbiology #microscopy ... fungus #comparison #table
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