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hematology differential algorithm management clinical allergy common cryofibrinogenemia cvid gangrenosum hemophilia hypogammaglobulinemia immunodeficiency immunology lad limping localized lymphadenopathy neutropenia nwb
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY RED FLAGS - In all cases there are specific markers which
FLAGS - In all cases ... guidelines General - Systemic ... cell disease Rheumatology ... #Peds #Pediatrics ... #Diagnosis
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Causes of Localized ... - Differential Diagnosis ... Tularemia • Secondary ... #Localized #Focal ... #Hematology #Oncology
Secondary Syphilis Rash Secondary syphilis is the most contagious of all the stages of this disease, and
characterized by a systemic ... resembling rashes caused ... #Rash #Diagnosis ... #Clinical #Photo ... #Dermatology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
an underlying cause ... frequently affected systems ... Better call hematology ... causes: Many of ... Algorithm #workup #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
processes: • Systemic ... Cryofibrinogenemia Diagnosis ... cryoglobulins • Negative causes ... #rheumatology # ... hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential Diagnosis ... syndrome Infant/child ... drug reactions - Secondary ... #differential #diagnosis ... #causes #hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
Hemophilia - Diagnosis ... normal in mild cases ... activity Mild: Local ... Avoid meds that ... Management #treatment #hematology
Approach to Elevated Tryptase - Differential Diagnosis Framework The DDx of elevated tryptase can be broken down
- Differential Diagnosis ... into a 4-pass system ... pass = Dangerous secondary ... #Differential #Diagnosis ... #hematology #allergy
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... late adulthood • Diagnosis ... hemolytic anemia) • Systemic ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
lacrimal glands: • Focal ... other diseases • Secondary ... Hypocomplementemia • Can cause ... Central nervous system ... Sjogrens #Syndrome #Rheumatology
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