8 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Approach to Thrombocytosis ... → Refer to hematology ... for workup, including ... Rebound effect from treatment ... Diagnosis #Algorithm #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
lymphocytes/Mature B cell ... or basket cells ... microglobulin Treatment ... Leukemia #diagnosis #workup ... #oncology #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... /µL Workup • Screen ... glucocorticoid treatment ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Workup: • Complete ... blood count with differential ... Syndromes #diagnosis #hematology ... #oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... • Induce blast cell ... initiation • Differential ... diagnosis #management #hematology ... #oncology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Approach to Joint ... Send for cell count ... Joint #Pain #MSK #rheumatology ... #approach #workup ... #differential #
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
Solitary Cell Plasmacytoma ... Bone marrow Treatment ... #Plasmacytoma #Oncology ... #Diagnosis #Workup ... #Hematology