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diagnosis signs management cellulitis endocrinology gh rheumatology syndrome als amyotrophic apex arteritis behcet causes clinical differential disease excess feedbackloop gait
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... /Symptoms: • GH ... expansion (e.g. carpal ... metabolic abn #GrowthHormone ... endocrinology #pathophysiology
Orbital Cellulitis: Pathogenesis and Clinical Findings Definitions: a. Chemosis: Edema of the bulbar conjunctiva b. Panopthalmitis: inflammation of all
Orbital Cellulitis ... #Cellulitis #pathophysiology ... #ophthalmology ... #diagnosis #signs ... #symptoms
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
overgrowth: • Carpal ... fraction • HTN #GrowthHormone ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Retinoblastoma: Pathogenesis and clinical findings • Sporadic mutation -> One allele of RB1 tumor suppressor gene
red reflex) • Orbital ... Retinoblastoma #pathophysiology ... #ophthalmology ... #diagnosis #signs ... #symptoms
Orbital Apex Syndrome secondary to Herpes Zoster Ophthalmicus (HZO) This 81 yo male was referred to our
fissure and optic canal ... receive proper treatment ... is no mainstay treatment ... clinical #video #ophthalmology ... #physicalexam #neurology
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 Optic Neuritis - Diagnosis and Management • Epidemiology: Female (75%), 18-50 years, caucasian • Symptoms: Moderate visual
caucasian • Symptoms ... /10), Moderate orbital ... Unilateral • Signs ... corticosteroids TREATMENT ... #rheumatology #ophthalmology
Periorbital Cellulitis: Pathogenesis and Clinical Findings Definitions: a. Dacryoadenitis: infection of the lacrimal glands b. Conjunctivitis: inflammation of the
preseptal compartment/orbital ... Periorbital #Cellulitis #pathophysiology ... #ophthalmology ... #diagnosis #signs ... #symptoms
Trendelenburg Gait: Pathogenesis and clinical findings Skeletal Pathology of the Hip • Arthritis • Congenital hip dysplasia
Chondrodysplasia Neurologic ... in the Spinal canal ... Trendelenburg #Gait #pathophysiology ... #causes #symptoms ... #signs #diagnosis
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... systemic sx + signs ... Treatment of GCA ... required +/- prompt ophthalmology ... GCA #Temporal #Signs
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... of UMN and LMN signs ... fasciculations Common Symptoms ... diagnosis column Treatment ... Lateral #Sclerosis #neurology
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