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diagnosis causes gh growthhormone treatment adrenal comparison congenitaladrenalhyperplasia diabetes diabeticketoacidosis differential dka excess feedbackloop management overproduction pediatrics peds pituitary signs
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
clinical findings • Acromegaly ... share the same pathophysiology ... overgrowth: • Carpal ... signs #symptoms #endocrinology ... #pathophysiology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
- Giantism or acromegaly ... expansion (e.g. carpal ... #FeedbackLoop #endocrinology ... #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
paresthesias (carpal ... decade → peripheral/acral ... malignancy Pathophysiology ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
Infographic depicting the main pearls of various types of congenital adrenal hyperplasia for the medical student.
#CAH #algorithm ... treatment #Peds #Endocrinology ... #Adrenal #pathophysiology
Tall Stature - Differential Diagnosis Algorithm Normal Growth (BA=CA) • Familial Tall Stature • XYY Syndrome Obese BMI
Differential Diagnosis Algorithm ... Normal Growth (BA=CA ... Resistance • Acromegaly ... Differential #Diagnosis #Algorithm ... #endocrinology
Acromegaly Testing Algorithm INDICATIONS FOR TESTING: • Adults – enlarged facial or acral features, abnormal musculoskeletal growth
Acromegaly Testing ... Algorithm INDICATIONS ... enlarged facial or acral ... #Testing #Algorithm ... #diagnosis #endocrinology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Diabetic Ketoacidosis ... besides glucose that can ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology
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