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diagnosis diabetes gh growthhormone causes diabetic diabeticketoacidosis differential excess feedbackloop highphosphate hyperphosphatemia ketoacidosis management overproduction pituitary signs symptoms testing treatment
Pathogenesis and Pathophysiology of Diabetic Ketoacidosis (DKA) DKA is a result of an absolute or relative insulin
Pathogenesis and Pathophysiology ... of carbohydrate metabolism ... state and fat metabolism ... #Pathophysiology ... #Diabetes #Endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
clinical findings • Acromegaly ... share the same pathophysiology ... overgrowth: • Carpal ... signs #symptoms #endocrinology ... #pathophysiology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
- Giantism or acromegaly ... expansion (e.g. carpal ... thickness) - metabolic ... #FeedbackLoop #endocrinology ... #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
paresthesias (carpal ... Hypogonad (50%) • Metabolic ... malignancy Pathophysiology ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
Hyperphosphatemia - Differential Diagnosis Algorithm Transcellular Shift: • Rhabdomyolysis • Tumor Lysis • Metabolic or Respiratory Acidosis
Differential Diagnosis Algorithm ... Tumor Lysis • Metabolic ... Pseudo-hypoparathyroidism • Acromegaly ... Differential #Diagnosis #Algorithm ... #endocrinology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Ketoacidosis (DKA ... Findings • Note: in DKA ... Due to neuronal metabolism ... #pathophysiology ... #endocrinology
Acromegaly Testing Algorithm INDICATIONS FOR TESTING: • Adults – enlarged facial or acral features, abnormal musculoskeletal growth
Acromegaly Testing ... Algorithm INDICATIONS ... enlarged facial or acral ... #Testing #Algorithm ... #diagnosis #endocrinology
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