13 results
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
Pathophysiology ... Hyperosmolar Syndrome (HHS ... Polydipsia #dka #hhs ... #pathophysiology ... #comparison #endocrinology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
expansion (e.g. carpal ... metabolic abn #GrowthHormone ... #FeedbackLoop #endocrinology ... #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... overgrowth: • Carpal ... fraction • HTN #GrowthHormone ... signs #symptoms #endocrinology ... #pathophysiology
Comparison of anti-diabetic or anti-hyperglycemic agents

There are numerous anti-hyperglycemic agents available to manage Type 2 diabetes.
Comparison of anti-diabetic ... manage Type 2 diabetes ... of medications has ... table #comparison #management ... #endocrinology
Ketosis Disorders - Comparison Table
 • Starvation Ketosis
 • Alcoholic Ketoacidosis (AKA)
 • Diabetic Ketoacidosis (DKA)
Ketoacidosis (AKA) • Diabetic ... Hyperosmolar State (HHS ... ) • DKA/HHS Overlap ... differential #diagnosis #management ... #endocrinology
Hyperglycemic Crisis - Algorithm for DKA/HHS

Diagnostic criteria for DKA:
 • pH < 7.3
 • Anion gap
Algorithm for DKA/HHS ... Diagnostic criteria for HHS ... Crisis #Algorithm #management ... #endocrinology ... #Diabetes #DM2 #
Euglycemic Diabetic Ketoacidosis (EuDKA)
SGLT2 Inhibitors
Increasing Indications
Significant Adverse Drug Effects
Definition of EuDKA
 • Metabolic acidosis with pH
Euglycemic Diabetic ... level < 200 mg/dL Pathophysiology ... #Euglycemic #Diabetic ... EuDKA #diagnosis #management ... #endocrinology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Diabetic Ketoacidosis ... ensure patient has ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology ... #diabetes
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Diagnosis and Management ... paresthesias (carpal ... malignancy Pathophysiology ... #Endocrinology ... #Treatment #Pathophysiology
Ketosis Disorders
Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
Diabetic ketoacidosis ... • DKA/HHS Overlap ... of both DKA & HHS ... differential #diagnosis #management ... #endocrinology