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diagnosis pituitary acromegaly algorithm causes differential excess feedbackloop glftap macroadenoma management masseffects mnemonic overproduction pediatrics shortstature sideeffects signs symptoms
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... expansion (e.g. carpal ... metabolic abn #GrowthHormone ... #endocrinology ... #pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... overgrowth: • Carpal ... fraction • HTN #GrowthHormone ... signs #symptoms #endocrinology ... #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
paresthesias (carpal ... malignancy Pathophysiology ... pseudo-acromegaly, obesity, hypothyroidism ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
Cushing's Disease • GH ... Dwarfism) • Hypothyroidism ... Panhypopituitarism Treatment ... Diagnosis #Algorithm #endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
adenomas that require treatment ... following order; GH ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
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