34 results
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
clinical findings • Acromegaly ... share the same pathophysiology ... rare causes of acromegaly ... overgrowth: • Carpal ... endocrinology #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
paresthesias (carpal ... decade → peripheral/acral ... malignancy Pathophysiology ... Differential Diagnosis ... Endocrinology #Treatment #Pathophysiology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
- Giantism or acromegaly ... expansion (e.g. carpal ... endocrinology #pathophysiology
Echinococcus Life Cycle
1) Adult in small intestine eggs
2) Embryonated egg in feces
3) Oncosphere hatches; penetrates intestinal
#Echinococcus #LifeCycle ... #diagnosis #pathophysiology ... #infectiousdiseases
Leishmaniasis Life Cycle
1) Sandfly takes a blood meal (injects promastigote stage into the skin)
Human Stages:
2) Promastigotes
Leishmaniasis #LifeCycle ... #diagnosis #pathophysiology ... #infectiousdiseases
Strongyloides fuelleborni Lifecycle
Free-Living Cycle
1) Eggs containing rhabditiform larvae passed in feces.
2) Rhabditiform larvae hatch in environment.
Strongyloides fuelleborni Lifecycle ... #fuelleborni #LifeCycle ... Parasite #diagnosis #pathophysiology ... #infectiousdiseases
Malaria - Plasmodium Life Cycle
1) Mosquito takes a blood meal (injects sporozoites)
Human Liver Stages
2) Infected liver
Malaria #Plasmodium #lifecycle ... #diagnosis #pathophysiology ... #infectiousdiseases
Babesiosis - Babesia Life Cycle
1) Tick takes a blood meal (sporozoites introduced into host)
2) Trophozie ←→
Babesiosis #Babesia #LifeCycle ... #diagnosis #pathophysiology ... #infectiousdiseases
Echinostomiasis - Echinostoma Life Cycle
1) Unembroynated eggs passed in feces
2) Embryonated eggs in water
3) Miracidia hatch
#Echinostoma #LifeCycle ... #diagnosis #pathophysiology ... #infectiousdiseases
Intestinal Hookworm Life Cycle
1) Eggs in feces
2) Rhabditiform larva hatches
3) Development to filariform larva in environment
4)
Hookworm #Intestinal #lifecycle ... #diagnosis #pathophysiology ... #infectiousdiseases