11 results
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... /Symptoms: • GH ... deficiency: ... expansion (e.g. carpal ... #FeedbackLoop #endocrinology
Cushing Syndrome - Signs and Symptoms
Generalized: Weight gain, Slow healing of cuts, Increased risk of infections,
Cushing Syndrome ... - Signs and Symptoms ... #Syndrome #Signs ... #Symptoms #diagnosis ... #endocrinology
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
Deprivation • Primary ... Endrocrine • Cushing's ... Disease • GH ... #Algorithm #endocrinology ... #causes #pediatrics
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
overgrowth: • Carpal ... Tunnel Syndrome ... Overproduction #diagnosis ... #signs #symptoms ... #endocrinology
Weight Gain / Obesity  - Differential Diagnosis Algorithm
Decreased Expenditure:
 • Sedentary Lifestyle
 • Smoking Cessation
- Differential Diagnosis ... Polycystic Ovarian Syndrome ... Hypothyroid • Cushing's ... • GH Deficiency ... #Algorithm #endocrinology
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
and signs. ... peripheries, Carpal ... timel syndrome, ... #Symptoms #Diagnosis ... #PhysicalExam #Endocrinology
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
include protein C deficiency ... Aldosterone Deficiency ... Serum DHEAS Diagnosis ... addisons #disease #endocrinology ... #diagnosis #signs
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
Cushing's Syndrome ... Hypercortisolism - Diagnosis ... not a feature of primary ... #Diagnosis #signs ... #symptoms #endocrinology
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings

Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
bladder filling pushing ... intrinsic sphincter deficiency ... Pathophysiology #Signs ... #Symptoms #Urology ... #Diagnosis
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
and Differential Diagnosis ... renal bruit or signs ... Vasculitis • Endocrinologic ... Hypothyroidism, Primary ... Hypercalcemia, Cushing's