55 results
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... skin lesions, ocular ... Zoster flare, ocular ... with severe symptoms ... #Inflammatory #Syndrome
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
IRIS might ... status, and focal neurologic ... and <25% culture positive ... patients with IRIS ... InfectiousDiseases #Neurology
Stages of Syphilis
Early Primary:
 • Painless chancre
 • Regional lymphadenopathy
Early Secondary:
 • Fever, malaise
 • Rash
Early Latent: • Positive ... testing • No symptoms ... first year of infection ... • Gummatous • Nodular ... Late Latent: • Positive
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Visual or auditory symptoms ... conjunction with symptoms ... • Enteroviral infections ... • Herpes virus infections ... #neurology #noninflammatory
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
desaturation, Scotoma, Ocular ... Other brainstem syndromes ... complications (AQP4-positive ... Manifestations #diagnosis #neurology ... #symptoms #signs
Neurological Manifestations of Tuberculosis
Spinal Arachnoiditis & Polyradiculopathy:
 • Subacute onset of limb weakness, bladder/bowel dysfunction, muscle
Reconstitution Inflammatory Syndrome ... (IRIS): • In HIV ... Worsening of previous neurologic ... and not direct infection ... differential #TB #neurology
Characteristic clinical manifestations of Down syndrome 
 
Typical craniofacial appearance 
 • Round face and flat
manifestations of Down syndrome ... Brushfield spots in iris ... susceptibility to infections ... impairment from cataracts ... #Downs #Syndrome
Blurry Vision - Differential Diagnosis Framework

Anatomical Approach to Eye Disease:
1. Lids/Lashes
2. Extraocular Muscles/Motility
3. Conjunctiva/Sclera
4. Cornea
5. Anterior
Iris 7. ... Trauma Cornea/Iris ... Uveitis Lens: • Cataracts ... • Sjögren’s syndrome ... hyperviscosity syndrome
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal Syndrome ... : - ANCA-positive ... allopurinol), Infection ... DAH, rule out infection ... differential #diagnosis #nephrology
Rheumatoid Arthritis - 2020 ACR-EULAR Classification
≥ 6 of 10 points = definite RA
Joint Involvement:
Arthritis - 2020 ACR-EULAR ... joint) - 5 points Serology ... RF or low positive ... points Duration of symptoms ... Arthritis #diagnosis #EULAR