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pharmacology nsaids comparison hereditaryspherocytosis nejm nsaid spherocytosis table acyclovir anesthesia brevibloc celebrex ckd clinical cox2inhibitor coxinhibitor cyclooxygenase disadvantages dosing drugs
NSAIDS and COX Selectivity Relative selectivity of some commonly used NSAIDs. Data shown as the logarithm of
NSAIDS and COX Selectivity ... Relative selectivity ... COX-1 Selectivity ... Piroxicam, Diclofenac, Celecoxib ... #pharmacology #selectivity
NSAID Selectivity Spectrum COX-2 Selective NSAID - Celecoxib • Increased risk for CV events • Decreased risk
NSAID Selectivity ... Selective NSAID - Celecoxib ... effects #NSAIDs #selectivity
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 Celecoxib. COX-2-specific NSAID, lower thrombembolic risk than rofecoxib and valdecoxib. Gabapentin - antiepileptic drug also used for
Celecoxib. ... #Pharmacology #Celecoxib
Therapeutic Advantages and Disadvantages of some NSAIDs Salicylates: Aspirin, Salicylate salts, Diflunisal Acetic acids: Indomethacin, Sulindac, Tolmetin Propionic acids:
-2 inhibitors: Celecoxib
Heparin and Low Molecular Weight Heparin (LMWH)–Mediated Inactivation of Thrombin or Factor Xa - Interaction
- LMWH selectively
Acyclovir - Pharmacology Summary • Mechanism of Action: Nucleoside analog - selectively inhibits viral replication of
Nucleoside analog - selectively
Hemolysis in Hereditary Spherocytosis. Panel A shows the structure of a normal red cell and a
ratio and are selectively
Sedative-Hypnotic Drugs Benzodiazepines: - Bind to specific GABAA receptor subunits at central nervous system (CNS) neuronal synapses
Hyponotics: - Bind selectively
NSAID Dosing in CKD • Carboxylic Acids: Salsalate, Choline Mg trisalicylate • Acetic Acids: Indomethacin, Tolmetin,
-2 Inhibitors: Celecoxib
Peripheral-Blood Smear. A peripheral-blood smear (Wright’s stain) shows spherocytes (selectively indicated by arrows). #Clinical #Pathology #Spherocytosis
shows spherocytes (selectively
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