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oncology management classification leukemia vasculitis allergy aplastic cll common cvid eosinophils hes hodgkins hypereosinophilia hypogammaglobulinemia immunodeficiency immunology lymphocytic lymphoma mcv
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... Hypereosinophilic Syndrome ... - Chronic Eosinophilic ... Diagnosis #Causes ... #hematology
Hypereosinophilia Syndrome (HES) - Diagnosis and Management Definition: An absolute eosinophil count (AEC) greater than 1500 and
(HES) - Diagnosis ... than 1500 and clinical ... Secondary Causes ... #diagnosis #hematology ... #differential #
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
- Differential ... malignancies • Anemia ... Myelodysplastic syndrome ... #Diagnosis #Causes ... #hematology #secondary
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Diagnostic Framework ... Myelodysplastic syndrome ... morphologic #mcv #differential ... #diagnosis #causes ... #hematology
Approach to Elevated Tryptase - Differential Diagnosis Framework The DDx of elevated tryptase can be broken down
Diagnosis Framework ... 2nd pass = Chronic ... ESRD & CAD • Eosinophilic ... cell activation syndrome ... #Diagnosis #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... and petechiae Causes ... - Hepatitis, eosinophilic ... #oncology #hematology ... #diagnosis #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... Physical Exam/Signs ... • Neutropenia, anemia ... workup #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... Out Secondary Causes ... Marrow Failure • Chronic ... blood count with differential ... #diagnosis #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... Autoimmunity • Chronic ... autoimmune hemolytic anemia ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Weight loss • Anemia ... Immunohistochemical studies (to differentiate ... through Ann Arbor criteria ... classification #hematology
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