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diagnosis algorithm differential management low treatment hypernatremia syndrome causes comparison hypokalemia hypotonic physiologic polydipsia primary saltwasting table uricacid volume workup
Cerebral Salt Wasting vs SIADH - Pathophysiology 1) Neurological event 2) Sodium loss from tubules 3) Naturiesis →
Cerebral Salt Wasting ... vs SIADH - Pathophysiology ... Neurological event 2) Sodium ... #diagnosis #nephrology ... #hyponatremia #
Modified Hyponatremia Algorithm Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants Hypotonic Hyponatremia: • ADH ON (UOsm > 100):
Modified Hyponatremia ... OFF (UNa > 30): SIADH ... Reset osmostat, Cerebral ... Algorithm #diagnosis #sodium ... #nephrology
Volume Based Approach to Hyponatremia Hypovolemic, Serum uric acid >4 • Urine Na <20: Extra-renal losses •
Based Approach to Hyponatremia ... Renal losses, Cerebral ... uric acid <4 • SIADH ... algorithm #diagnosis #sodium ... #low #nephrology
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... Osmolarity 3) Urine Sodium ... Low Uric Acid → SIADH ... Diagnosis #Algorithm #nephrology ... #sodium #low #uricacid
Hypernatremia Diagnosis and Workup Step 1 . Repeat the sodium concentration. Step 2. Check plasma osmolality. NORMAL PLASMA
Hypernatremia Diagnosis ... Repeat the sodium ... mmol/L - true hyponatremia ... EUVOLEMIC • SIADH ... Workup #Algorithm #Nephrology
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
restriction alone in SIADH ... Present (Uosm ≥100): SIADH ... , Renal Sodium loss ... Insufficiency, Cerebral ... #nephrology
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... thiazide-sensitive sodium-chloride ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Hyponatremia - Differential Diagnosis Algorithm Hypovolemic - Give volume Hypervolemic (Edematous) - Look for and treat underlying cause
Hyponatremia - Differential ... , SSRIs) - SIADH ... UnremarkableLab #Hyponatremia ... Algorithm #diagnosis #nephrology ... #sodium
Management of SIADH Treat underlying cause: • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
Management of SIADH ... promoting passive sodium ... SatyaPatelMD #SIADH ... #Management #hyponatremia ... #nephrology #treatment
Hyponatremia - Differential Algorithm Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP Hypotonic Hyponatremia: • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
Hyponatremia - Differential ... Algorithm Isotonic Hyponatremia ... • Euvolemia: SIADH ... diagnosis #causes #nephrology ... #sodium #low
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