8 results
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Diagnosis: • Clinical ... non-heparin A/C if clinical ... Can consider re-challenge ... #Treatment #Hematology ... #HemeOnc
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... Petechiae • Purpura ... deficiency) • HIT ... + Bleeding Treatment ... #management #hematology
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
+purpuric rash → ... purpura fulminans ... inflammation persist → DIC ... possible Patient's clinical ... #dermatology #clinical
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... arthritis, Skin rash ... MAS, Visceral, DIC ... Disease #diagnosis #management ... #treatment #rheumatology
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Diagnosis and Management ... poor nutrition Clinical ... deficiencies • Vit ... • DIC • Rocky ... vasculitis Treatment
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
pain, dark urine, DIC ... maculopapular rash ... Post Transfusion Purpura ... Causes purpura & ... Transfusion #diagnosis #management
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
pain, dark urine, DIC ... maculopapular rash ... Post Transfusion Purpura ... Causes purpura & ... Transfusions #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
easy bruising to purpura ... (Petechial or purpuric ... rash) • Heart, ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management