8 results
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
- Differential ... Normochromic RBCs on Smear ... • Chronic Bleed ... • Anemia of Chronic ... Spherocytes on Smear
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Volume (MCV) - Differential ... Normal Blood Smear ... RBCs in Rouleaux ... #elevatedMCV #Differential ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Chronic disease ... Multiple myeloma Rouleaux ... : Chronic liver ... RBC #Morphology #differential ... #diagnosis #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Peripheral Smear ... hemolysis, deficiency anemia ... • Infections: Chronic ... Thrombocytosis #Platelets #Differential
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... • Peripheral smear ... immunophenotype Clinical ... 5) Symptoms of anemia ... marrow failure with anemia
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... • Symptoms of anemia ... IgM) • Blood smear ... younger pts) Differential ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... • Peripheral smear ... • Neutropenia, anemia ... leukemia #CLL #Chronic
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Peripheral Smear ... Marrow Failure • Chronic ... blood count with differential ... Peripheral blood smear ... Syndromes #diagnosis #hematology