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hematology management oncology leukemia algorithm cll differential lymphocytic alkaline alp approach babesia babesiosis bacilliformis bartonella classification coagulation common cvid dic
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Normal Blood Smear ... RBCs in Rouleaux ... Formation • Multiple ... #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... • Chronic Bleed ... • Anemia of Chronic ... #Algorithm #Causes ... #Hematology
Indications for Serum Protein Electrophoresis (SPEP) • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
• New-onset anemia ... bleeding) • Rouleaux ... formations noted ... peripheral blood smear ... #Diagnosis
Oroya Fever Hematologic disease caused by Bartonella bacilliformis Restricted to the Andes highlands of Peru & Ecuador B. bacilliformis:
Hematologic disease caused ... Lutzomyia verrucarum Clinical ... severe hemolytic anemia ... Nodular → Mular DIAGNOSIS ... phase: Peripheral smear
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... • Peripheral smear ... immunophenotype Clinical ... 5) Symptoms of anemia ... #hemeonc #diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... -> AML: Blast crises ... - infiltrates (anemia ... • Peripheral smear ... #Oncology #Diagnosis
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... Most cases diagnosed ... thigh bones -> chronic ... • Pernicious anemia ... Phosphatase: • Other causes
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
organ damage Clinical ... • Peripheral smear ... significant fibrin clot formation ... #Coagulation #diagnosis ... #causes #treatment
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... phenomenon CLL Diagnosis ... • Peripheral smear ... • Neutropenia, anemia
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Peripheral Smear ... Marrow Failure • Chronic ... Peripheral blood smear ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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