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hematology management causes cll leukemia lymphocytic oncology algorithm babesia babesiosis blood coagulation common cvid dic differential disseminated electrophoresis elevatedmcv hemeonc
Autoagglutination should also be distinguished from “Rouleaux formation” wherein normal blood tends to form stacks on
formation” wherein ... when the plasma protein ... #Clinical #Pathology ... #Blood #Smear # ... #Formation #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... Normal Blood Smear ... RBCs in Rouleaux ... Formation • Multiple ... #Differential #Diagnosis
Indications for Serum Protein Electrophoresis (SPEP) • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
• New-onset anemia ... bleeding) • Rouleaux ... formations noted ... peripheral blood smear ... #Diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... • Peripheral smear ... immunophenotype Clinical ... 5) Symptoms of anemia ... #hemeonc #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
antithrombin, protein ... organ damage Clinical ... • Peripheral smear ... significant fibrin clot formation ... #Coagulation #diagnosis
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... Autoimmunity • Chronic ... autoimmune hemolytic anemia ... syndrome • Burns • Protein-losing ... Malignancies • Chronic
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... phenomenon CLL Diagnosis ... • Peripheral smear ... • Neutropenia, anemia
Babesiosis on Peripheral Smear 85 M from SE USA, hx splenectomy, IgG4 plasmacytic syndrome: F, chills, profound
hematuria, H/A. diagnosis ... inclusions, improved clinically ... and spur cells, +rouleoux ... formation Splenectomized ... lysis: fever, anemia
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