12 results
Rouleaux formation is common in IgM gammopathy and may be particularly striking

Genevieve Crane, MD, PhD@evemariecrane

#Rouleaux #formation
Rouleaux formation ... #formation #IgM ... gammopathy #MGUS #Clinical ... #Pathology #Hematology ... #Smear
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
with extensive rouleaux ... formation. ... PlasmaCell #leukemia #rouleaux ... #formation #Clinical ... #Smear #Hematology
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA
Warm AIHA:
 - 70%; IgG mediated
 -
Autoimmune Hemolytic Anemia ... or negative - Smear ... agglutination, rouleaux ... Pathophysiology #diagnosis ... #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
- Differential Diagnosis ... Normal Blood Smear ... RBCs in Rouleaux ... Formation • Multiple ... #Differential #Diagnosis
Autoagglutination should also be distinguished from “Rouleaux formation” wherein normal blood tends to form stacks on
distinguished from “Rouleaux ... formation” wherein ... #Clinical #Pathology ... #Blood #Smear # ... #Formation #Hematology
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
DIC is a clinical ... and laboratory diagnosis ... arrow) Peripheral smear ... #Hematology #Pathology ... #Smear #Microscopy
Indications for Serum Protein Electrophoresis (SPEP)
 • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
• New-onset anemia ... bleeding) • Rouleaux ... formations noted ... peripheral blood smear ... #Diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... • Peripheral smear ... immunophenotype Clinical ... 5) Symptoms of anemia ... #hemeonc #diagnosis
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... • Symptoms of anemia ... anemia • Cold ... IgM) • Blood smear ... #hematology #diagnosis
Babesiosis on Peripheral Smear
85 M from SE USA, hx splenectomy, IgG4 plasmacytic syndrome: F, chills, profound
hematuria, H/A. diagnosis ... inclusions, improved clinically ... and spur cells, +rouleoux ... formation Splenectomized ... lysis: fever, anemia