56 results
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA
Warm AIHA:
 - 70%; IgG mediated
 -
Autoimmune Hemolytic Anemia ... or negative - Smear ... C3 positive - Smear ... agglutination, rouleaux ... Pathophysiology #diagnosis #hematology
Rouleaux formation is common in IgM gammopathy and may be particularly striking

Genevieve Crane, MD, PhD@evemariecrane

#Rouleaux #formation
Rouleaux formation ... evemariecrane #Rouleaux ... gammopathy #MGUS #Clinical ... #Pathology #Hematology ... #Smear
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
with extensive rouleaux ... PlasmaCell #leukemia #rouleaux ... #formation #Clinical ... #Smear #Hematology
Sickle cell anemia and Howell Jolly bodies (nuclear remnants).

 - Dr. Abubaker Elshaikh
@ElshaikhMD

#SickleCell #HowellJolly #Body #Bodies
Sickle cell anemia ... Bodies #Pathology #Hematology ... #Smear #Clinical
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Peripheral Blood Smear ... Peripheral #Blood #Smear ... #Analysis #hematology ... interpretation #clinical ... #anemia
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... Algorithm Signs of anemia ... Abnormal peripheral smear ... #Hemolytic #Anemias ... Diagnosis #Algorithm #hematology
Laboratory Testing in Hemolytic Anemia

Intravascular vs Extravascular Hemolysis
Reticulocytes
Unconjugated bilirubin
LDH
Peripheral smear
Haptoglobin
Urine hemosiderin
Urine hemoglobin
Carboxyhemoglobin

#Hemolytic #Anemia #Laboratory #Testing #workup
Testing in Hemolytic Anemia ... LDH Peripheral smear ... #Hemolytic #Anemia ... workup #diagnosis #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Normal Blood Smear ... • Pernicious Anemia ... RBCs in Rouleaux ... Algorithm #Causes #Hematology
Leukoerythroblastosis and myelophthisic anemia can be associated with any marrow-replacing process. In this case, the likely
myelophthisic anemia ... Leukoerythroblastosis #Hematology ... #Pathology #Smear ... #Microscopy #Clinical
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
microangiopathic hemolytic anemia ... DIC is a clinical ... arrow) Peripheral smear ... #Hematology #Pathology ... #Smear #Microscopy