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hematology pathology blood diagnosis microscopy anemia babesia babesiosis causes coagulation dic disseminated electrophoresis gammopathy igm indications interpretation intravascular leukemia management
Rouleaux formation is common in IgM gammopathy and may be particularly striking Genevieve Crane, MD, PhD@evemariecrane #Rouleaux #formation
Rouleaux formation ... #formation #IgM ... gammopathy #MGUS #Clinical ... #Pathology #Hematology ... #Smear
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
with extensive rouleaux ... formation. ... PlasmaCell #leukemia #rouleaux ... #formation #Clinical ... #Smear #Hematology
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Peripheral Blood ... Smear Analysis ... #Blood #Smear # ... Analysis #hematology ... interpretation #clinical
Autoagglutination should also be distinguished from “Rouleaux formation” wherein normal blood tends to form stacks on
distinguished from “Rouleaux ... formation” wherein ... #Clinical #Pathology ... #Blood #Smear # ... #Formation #Hematology
Indications for Serum Protein Electrophoresis (SPEP) • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
• Unexplained peripheral ... bleeding) • Rouleaux ... formations noted ... on peripheral blood ... smear • Renal
Babesiosis on Peripheral Smear 85 M from SE USA, hx splenectomy, IgG4 plasmacytic syndrome: F, chills, profound
Babesiosis on Peripheral ... inclusions, improved clinically ... and spur cells, +rouleoux ... formation Splenectomized ... #microti #clinical
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
organ damage Clinical ... D-Dimer: ↑ • Peripheral ... smear: Schistocytes ... significant fibrin clot formation ... treatment #management #hematology
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