9 results
Rouleaux formation is common in IgM gammopathy and may be particularly striking

Genevieve Crane, MD, PhD@evemariecrane

#Rouleaux #formation
Rouleaux formation ... common in IgM gammopathy ... #MGUS #Clinical ... #Pathology #Hematology ... #Smear
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
with extensive rouleaux ... PlasmaCell #leukemia #rouleaux ... #formation #Clinical ... #Smear #Hematology
Autoagglutination should also be distinguished from “Rouleaux formation” wherein normal blood tends to form stacks on
distinguished from “Rouleaux ... #Clinical #Pathology ... #Blood #Smear # ... Microscopy #Rouleaux ... #Formation #Hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
• Peripheral smear ... immunophenotype Clinical ... transformation) Treatment ... AIHA, PRCA) • Treatment ... Leukemia #oncology #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... IgM) • Blood smear ... IgM monoclonal gammopathy ... hemolytic #anemia #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Diagnosis: • Clinical ... non-heparin A/C if clinical ... Can consider re-challenge ... Diagnosis #Management #Treatment ... #Hematology #HemeOnc
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... • Peripheral smear ... + Bleeding Treatment ... diagnosis #causes #treatment ... #management #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... • Peripheral smear ... microglobulin Treatment ... workup #oncology #hematology
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS)
Fracture, Osteoporosis
 - Increased osteoclast activity and bone resorption
of Monoclonal Gammopathy ... antibody - Early treatment ... rituximab (in clinical ... MGUS #Monoclonal #Gammopathy ... Complications #diagnosis #hematology