12 results
Autoimmune Hemolytic Anemia (AIHA) Pathophysiology - Warm vs Cold AIHA
Warm AIHA:
 - 70%; IgG mediated
 -
or negative - Smear ... C3 positive - Smear ... agglutination, rouleaux ... Pathophysiology #diagnosis ... #hematology
Rouleaux formation is common in IgM gammopathy and may be particularly striking

Genevieve Crane, MD, PhD@evemariecrane

#Rouleaux #formation
Rouleaux formation ... is common in IgM ... gammopathy #MGUS #Clinical ... #Pathology #Hematology ... #Smear
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... Diagnosis: • hemolytic ... ) • Blood smear ... hemolytic #anemia #hematology ... #diagnosis
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Pathophysiology: • IgG ... : • Clinical Suspicion ... Can consider re-challenge ... #Management #Treatment ... #Hematology #HemeOnc
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... • Peripheral smear ... immunophenotype Clinical ... Leukemia #oncology #hematology ... #hemeonc #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... • Peripheral smear ... + Bleeding Treatment ... #Coagulation #diagnosis ... #causes #treatment
Borrelia recurrentis on Peripheral Blood Smear
23M Somali refugee recently arrived w/severe abd pain, confusion and fever
LBRF can be diagnosed ... can be used for diagnosis ... or PenG 800K U IM ... initiation of treatment ... microscopy #pathology #clinical
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... phenomenon CLL Diagnosis ... • Peripheral smear ... microglobulin Treatment ... Lymphocytic #Leukemia #diagnosis
Chagas Disease (American trypanosomiasis) - Diagnosis and Management Summary
Acute Chagas Disease (8-12 weeks):
 • Mild: Malaise,
detectable by blood smears ... • Treatment: ... is confirmed by IgG ... Disease": T. cruzi + clinical ... T.cruzi without clinical
Monkeypox

What?
Monkeypox virus belongs to the family Poxviridae, subfamily Chordopoxvirinae, and genus orthopoxvirus
Viral zoonotic disease that is
three weeks Clinical ... antiorthopoxvirus IgM ... Respiratory distress Treatment ... Monkeypox #MPOX #Diagnosis ... #Management #Dermatology