6 results
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Hepatocellular: Viral infections ... disease, Hepatic ... or incomplete dechallenge ... presentation: Hepatic ... disorder (e.g. ascites
Causes of Ascites - Differential Diagnosis Algorithm
Portal Hypertension - Prehepatic:
 • Portal vein thrombosis
 • Splenic
- Differential ... Hypertension - Hepatic ... disease • Acute liver ... Primary biliary cholangitis ... #Differential #
Deciphering the SAAG - Serum to Ascites Albumin Gradient
Ascites is either made in the liver sinusoid
either made in the liver ... or not by the liver ... source: Malignancy, Infection ... liverprof #Diagnosis #Hepatology ... Interpretation #Differential
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Liver disease ... - Acute fatty liver ... SAAG < 1.1 g/dL) Infections ... Causes #diagnosis #differential ... #hepatology #SAAG
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
cholestasis → Cirrhosis/Liver ... or higher • Liver ... bile ducts Differential ... malignancies, Hepatic ... fungal, viral infections
Pyogenic liver abscess in children
Common bacterial causes in children:
 • S.aureus
 • Strep spp
 • Enteric
Pyogenic liver abscess ... Biliary tree (cholangitis ... through: - Hepatic ... children #peds #differential ... #diagnosis #hepatology