9 results
Fungal biomarkers
Beta-d-glucan
Aspergillus galactomannan

By Dr. Sara Dong @swinndong via Febrile [febrilepodcast.com]

#ID  #Infectious Diseases  #Infections
#Differential #Ddx
Beta-d-glucan Aspergillus ... galactomannan ... febrilepodcast.com] #ID ... #Infections #Differential ... Diagnosis #Fungal #Fungi
Transplant Infections Timeline
Pre-transplant:
 • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut)
 • Viruses: HSV (reactivation)
Engraftment:
Transplant Infections ... (mucosa), Aspergillus ... : Aspergillus spp ... #Timeline #differential ... diagnosis #causes #infectiousdiseases
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
component of many fungi ... invasive fungal infection ... BAL GM does not differentiate ... closely related fungi ... setting of GVHD) ID
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives
1,3-Beta-D-Glucan
 • Cell wall component of many fungi
Beta-D-Glucan and Galactomannan ... component of many fungi ... surfaces, Albumin, Infections ... in BAL does not differentiate ... closely related fungi
Causes of Culture Negative Abscess - Differential Diagnosis Framework
Consider prior antibiotics as a cause of a
Negative Abscess - Differential ... Scedosporium, endemic fungi ... Dracunculiasis - Non-Infectious ... Blastomycosis - Non-Infectious ... #Diagnosis #InfectiousDiseases
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
fastidious bacteria or fungi ... Tropheryma whipplei, Fungi ... (Aspergillus, Candida ... Endocarditis #diagnosis #differential ... #workup #infectiousdiseases
Soil Related Infections - Differential Diagnosis Framework

Mechanism Of Infection:
 • Wound
 • GI: Ingestion, MUD, Contaminated
- Differential ... include: bacteria, fungi ... pulmonary disease • Aspergillus ... #differential # ... diagnosis #InfectiousDiseases
Concurrent Brain and Lung Lesions
 • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
) • Fungi: Aspergillus ... #Brain #Lung #Infections ... #Concurrent #Differential ... Diagnosis #causes #infectiousdiseases
Concurrent Brain and Lung Lesions
 • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
) • Fungi: Aspergillus ... #Brain #Lung #Infections ... #Concurrent #Differential ... Diagnosis #causes #infectiousdiseases