13 results
Fungal biomarkers
Beta-d-glucan
Aspergillus galactomannan

By Dr. Sara Dong @swinndong via Febrile [febrilepodcast.com]

#ID  #Infectious Diseases  #Infections
#Differential #Ddx
Beta-d-glucan Aspergillus ... febrilepodcast.com] #ID ... #Infectious Diseases ... #Infections #Differential ... Diagnosis #Fungal #Fungi
Transplant Infections Timeline
Pre-transplant:
 • Common bacteria (endogenous): Staphylococci (skin), Gram-negative bacilli (gut)
 • Viruses: HSV (reactivation)
Engraftment:
Transplant Infections ... (mucosa), Aspergillus ... : Aspergillus spp ... #Timeline #differential ... diagnosis #causes #infectiousdiseases
Microorganisms Responsible for Infective Endocarditis

Native valves:
 - Streptococcus viridans 
 - Enterococci 
 - Other streptococci
bacilli - Fungi ... (Candida, Aspergillus ... bacilli - Fungi ... Pathogens #Diagnosis #Differential ... #InfectiousDiseases
Causes of Culture Negative Abscess - Differential Diagnosis Framework
Consider prior antibiotics as a cause of a
Abscess - Differential ... Scedosporium, endemic fungi ... Dracunculiasis - Non-Infectious ... #Abscess #Differential ... #Diagnosis #InfectiousDiseases
Causes of Secondary Amenorrhea - Differential Diagnosis Algorithm
Absence of menses for more than 3 cycles or
Causes of Secondary Amenorrhea ... - Differential ... Hypothalamic - Negative ... Radiation • Infection ... #Differential #
Causes of blood culture negative infective endocarditis

Bartonella spp, Brucella spp, Coxiella burnetii, Chlamydia spp, Tropheryma whipplei,
blood culture negative ... Tropheryma whipplei, Fungi ... (Aspergillus, Candida ... BCNIE #Causes #differential ... #Endocarditis #InfectiousDiseases
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan
Beta-D-Glucan:
 • Polysaccharide cell wall component of many fungi
 • Pathogens:
component of many fungi ... Coccidioides - Negative ... invasive fungal infection ... BAL GM does not differentiate ... setting of GVHD) ID
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
Blood Culture-Negative ... cultures remain negative ... (Aspergillus, Candida ... Endocarditis #diagnosis #differential ... #workup #infectiousdiseases
Soil Related Infections - Differential Diagnosis Framework

Mechanism Of Infection:
 • Wound
 • GI: Ingestion, MUD, Contaminated
- Differential ... include: bacteria, fungi ... pulmonary disease • Aspergillus ... #differential # ... diagnosis #InfectiousDiseases
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives
1,3-Beta-D-Glucan
 • Cell wall component of many fungi
component of many fungi ... Almost always negative ... surfaces, Albumin, Infections ... in BAL does not differentiate ... closely related fungi