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diagnosis hematology causes algorithm eosinophilia oncology basophilia fever immunecompromised immunocompromised leukemia mds myelodysplasia myelodysplastic syndromes tryptase
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Basophilia - Differential ... released during an allergic ... reaction or asthma ... Disorders: • Chronic ... #Differential #
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... pain, bleeding, infections ... eosinophilia, basophilia ... or functional neutropenia ... #Leukemia #Hematology
Eosinophilia - Differential Diagnosis Algorithm Idiopathic Eosinophilia Primary Eosinophilia: • Primary hypereosinophilic syndrome • Eosinophilic Leukemia • MPN/MDS
Eosinophilia - Differential ... histiocytosis • Allergic ... : Asthma, Eczema ... eosinophilia) • Infectious ... insufficiency, Chronic
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
Eosinophilia - Differential ... Rhinitis - Allergic ... Dermatitis - Asthma ... Primary: - CML ... Hypereosinophilic Syndrome - Chronic
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm Structural Defect - Asplenia/HypospIenism • Bacteremia/Septic
Immunocompromised Host - Differential ... Encapsulated Bacteria Cell ... Neutropenia or ... Bronchitis • Chronic ... Algorithm #Causes #Hematology
Approach to Elevated Tryptase - Differential Diagnosis Framework The DDx of elevated tryptase can be broken down
2nd pass = Chronic ... • Parasitic infections ... Causes: • Mast cell ... #Diagnosis #hematology ... #allergy
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
petechiae) • Frequent infections ... Marrow Failure • Chronic ... Myeloproliferative Disease • Neutropenia ... • Parvovirus infection ... blood count with differential
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