12 results
diagnosis causes oncology anemia hemolytic leukemia algorithm lymphocytic workup allergy basophilia cold disease extravascular fever hemeonc hemolysis immunecompromised immunocompromised intravascular
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Basophilia - Differential ... Myeloproliferative Disorders ... : • Chronic myeloid ... #Differential # ... Diagnosis #causes #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
lymphoproliferative disorder ... , autoimmune disorder ... malignancies -> CLL ... younger pts) Differential ... hemolytic #anemia #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Malaise, bleeding, infections ... pain, bleeding, infections ... eosinophilia, basophilia ... or functional neutropenia ... #Leukemia #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
thalassemia, S Lepore • Basophilic ... Agglutination - Cold agglutinins ... inclusions - If infection ... Consider RBC membrane disorder ... Algorithm #workup #hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential ... Diagnosis Neonate: - Infection ... including white blood cell ... #differential # ... diagnosis #causes #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis - Differential ... Thrombocytosis): • Acute infection ... inflammatory disorders ... myeloid leukemia (CML ... Diagnosis #Causes #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
) (e.g. lupus, CLL ... . primary cold agglutin ... lymphoproliferative disorders ... Extravascular #Causes #differential ... #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... weeks without infection ... lymphoproliferative disorders ... Cytopenias: • Neutropenia ... workup #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... leukemia in adults • Disorder ... Complications: 1) Infection ... PRCA, autoimmune neutropenia ... Leukemia #oncology #hematology
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm Structural Defect - Asplenia/HypospIenism • Bacteremia/Septic
Immunocompromised Host - Differential ... Encapsulated Bacteria Cell ... Neutropenia or ... Bronchitis • Chronic ... Algorithm #Causes #Hematology
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