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causes workup algorithm bruising classification dermatology hemolysis intravascular nonpalpable palpable rheumatology testing thromboticthrombocytopenicpurpura ttp
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
coagulation (DIC) - HELLP ... purpura (TTP), ... syndrome (HUS) ... #Causes #differential ... #diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - DIC, TTP, HELLP ... , HUS, aHUS, mechanical ... #Anemia #Differential ... #workup #hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... • MAHA: TTP, HUS ... , DIC, HELLP, AS ... #Anemia #Differential
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... - Hemolytic ... anemia - Splenomegaly ... Diagnosis #hematology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Non-immune - Haemolytic ... (disseminated intravascular ... Bruising #Causes #peds ... #pediatrics #diagnosis ... #differential #
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... Purpura Activity ... anemia Indirect ... WBC count and differential ... #Workup #Hematology
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