11 results
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
- Pharmacology ... normally inactivates GLP ... combination therapy with GLP-I ... #Inhibitors #Pharmacology ... DM2 #diabetes #endocrinology
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
They work primarily ... upset (since it works ... very similar to DPP4s ... #Pharmacology #Dosing ... Diabetes #DM2 #Endocrinology
Mechanism of Action for Common Diabetes Medications

 • SGLT2i (Dapagliflozin)
 • TZD (Pioglitazone)
 • Biguanides (Metformin)
Meglitinides • GLP ... Receptor Agonists • DPP4i ... #Medications #pharmacology ... pathophysiology #endocrinology
Diabetes Medications Summary Table
Insulin
Lifestyle modifications
Metformin
Sulfonylureas
GLP-1 receptor agonists - ↓ major adverse CV events
TZDs
DPP-4 inhibitors
SGLT2 inhibitors -
Medications Summary Table ... Sulfonylureas GLP ... events TZDs DPP ... #medications #table ... comparison #management #endocrinology
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
DPP4 Inhibitors ... Increase Incretins (GLP-I ... inhibitors work ... Renal #Dosing #Pharmacology ... Diabetes #DM2 #Endocrinology
REBEL Review 46: Corticosteroid Conversion Chart 

Glucocorticoid, Approximate Equivalent Dose (mg), Relative Anti-Inflammatory (Glucocorticoid) Potency, Relative
Corticosteroid Conversion Chart ... steroid #conversion #endocrinology ... #comparison #table ... #pharmacology #
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
GLP-1 Receptor Agonists ... - Pharmacology ... Ozempic), or daily tablet ... Receptor #Agonists #Pharmacology ... DM2 #diabetes #endocrinology
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist
Dosing:
3 mg daily x 30 days, then 7 mg
Otherwise, it works ... drug to remain stable ... empagliflozin and DPP4 ... semaglutide #Diabetes #Pharmacology ... #Endocrinology
Comparison of anti-diabetic or anti-hyperglycemic agents

There are numerous anti-hyperglycemic agents available to manage Type 2 diabetes.
This chart summarizes ... #pharmacology #pharmacotherapy ... #table #comparison ... medications #diabetes #endocrinology
Insulin Comparison Chart

Insulin Types - Onset (hours) - Peak Glycemic Effect (hours) - Duration (hours)
 •
Insulin Comparison Chart ... Insulin #Comparison #Table ... #pharmacology # ... diabetes #endocrinology