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management rheumatoidarthritis rheumatology anorexianervosa complications cop cppd cryptogenic differential diffuse endocrinology extraarticular fungal gout hyperparathyroidism infections infectiousdiseases mycoses organizing pneumonia
Hyperparathyroidism - Primary vs Secondary vs Tertiary Lab Comparison: • Primary Hyperparathyroidism: ↑→PTH, ↑Calcium, ↑Vitamin D,
Tertiary Lab Comparison ... : Commonly no signs ... Alteration in hunger ... Hyperparathyroidism #diagnosis ... Secondary #Tertiary #pathophysiology
Sarcoidosis Non-caseating granulomas (Composed of T-helper & inflammatory cells) Clinical: • Disease fatal in 10% of
fatal in 10% of pts ... exertion • Neurologic ... #Sarcoidosis #Diagnosis ... #Symptoms #Signs ... #Pulmonary
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Rheumatoid arthritis (RA ... interstitial lung disease/pulmonary ... #pathophysiology ... #signs #symptoms ... #diagnosis #ExtraArticular
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
ulnar drift of fingers ... Extra-articular signs ... #pathophysiology ... #signs #symptoms ... #diagnosis
Diffuse Systemic Sclerosis (Scleroderma) - Pulmonary Fibrosis -> Crackles, Abnormal CXR - Pulmonary Hypertension, Right Heart
Scleroderma) - Pulmonary ... Abnormal CXR - Pulmonary ... #Scleroderma #pathophysiology ... #signs #symptoms ... #diagnosis
Cryptogenic Organizing Pneumonia - Illness Script PATHOPHYSIOLOGY: Unknown trigger, reversible inflammatory/fibroproliferative process. Polypoid fibroblastic aggregates that plug
Illness Script PATHOPHYSIOLOGY ... Males=Females SIGNS ... /SYMPTOMS: • Acute ... misdiagnosed as CAP • Symptoms ... #management #pulmonary
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
disease states Pathophysiology ... Arthritis: Resembles RA ... culture used to diagnose ... ankles, knees, fingers ... #CPPD #Gout #Comparison
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... May develop in pts ... affects the skin, neurologic ... • Progressive symptoms
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
by culture or serology ... A. flavus, A. niger ... Aspergillosis Pathophysiology ... : • Serology for ... scalp, vagina, fingers
Anorexia Nervosa: Complications CARDIAC ABNORMALITIES - Functional: Low BP, Sinus bradycardia, prolonged QT interval - Structural: Reduced
/ Hypovolemia NEUROLOGIC ... skin) - Lanugo: fine ... Complications #pathophysiology ... #diagnosis #signs ... #symptoms #psychiatry
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