11 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... of Systemic Lupus ... Demyelinating Syndrome, Headache ... disorders, Aseptic Meningitis ... #SLE #CNS #neurology
Photophobia and Headache - Differential Diagnosis Framework

Why?
• The coexistence of photophobia and headache suggests the potential
- Differential Diagnosis ... glaucoma - Ocular ... • CNS Vasculitis ... #ophthalmology ... #Neurology
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
- Differential Diagnosis ... pupil (AACG) • Systemic ... brain lesion • CNS ... infection (e.g., meningitis ... #Algorithm #neurology
Headache Etiologies and Associated Spectrum of Severity of Disease by System
Critical, Emergent and Non-Emergent Causes
CNS, neurologic,
Headache Etiologies ... of Disease by System ... Non-Emergent Causes CNS ... vascular disease Ocular ... #differential #diagnosis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome Systemic ... skin injury) • Neurologic ... lesions, aseptic meningitis ... (headache and diplopia ... inhibitors • Uveitis- Ophthalmology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
et diutinum Neurologic ... neuropathy) • Systemic ... Hypergammaglobulinemic macular ... to cold IgG • Lupus ... #Differential #Diagnosis
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
desaturation, Scotoma, Ocular ... pain • Extra-CNS ... lupus erythematosus ... Manifestations #diagnosis ... #neurology #symptoms
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Erythematous, macular ... Differential Diagnosis ... and CNSHeadache ... PAC • Aseptic meningitis
Headaches Overview - Primary vs Secondary Headaches

What’s the Core Difference?
 • Primary headache = headache is
Infection (e.g., meningitis ... Thunderclap) • Meningitis ... Features (SNOOP): S Systemic ... Primary #Secondary #Comparison ... #Neurology #Diagnosis
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
cough, chills, headache ... or meningitic disease ... especially the CNS ... MC: CNS CSF: • ... osteoarticular, pulmonary, ocular