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diagnosis hematology differential algorithm secondary workup cell classification elevatedmcv extravascular hemolysis hemolytic hodgkins intravascular lymphoma macrocytic macrocytosis management mds myelodysplasia
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cryoglobulin (CG ... cryoglobulinemia Associated Disorders ... sensitivity • Painful ... reticularis • Painful ... cryoglobulins • Negative causes
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... halt nail growth (e.g ... lines, usually painful ... Systemic #Secondary #dermatology ... Diagnosis #Algorithm #causes
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
and Platelet Disorders ... function test, ANA (e.g ... changes), high MCV anemia ... primary hematologic disorder ... #Workup #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... malignancies • Anemia ... Chronic inflammatory disorders ... (e.g. autoimmune ... #hematology #secondary
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... Microangiopathic hemolytic anemia ... lymphoproliferative disorders ... Extravascular #Causes ... #anemia
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Increased Requirement (e.g ... • Small Bowel Disorder ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
Causes of Neutropenia ... the most common cause ... , eg, cyclic neutropenia ... Megaloblastic anemia-rare ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... caused by blood ... skin that are caused ... Neutropenia • Platelet Disorders ... #oncology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Rare Disorder: ... onset of tender or painful ... Causes: - Idiopathic ... Syndrome #diagnosis #dermatology ... #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... Weight loss • Anemia ... Immune hemolytic anemia ... classification #hematology ... #oncology #management
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